Nootropic drug. Colorless clear liquid.
Indications
intellectual and memory disorders in vascular lesions of the brain;
recovery period after stroke;
dyscirculatory encephalopathy;
transient ischemic attacks (TIA);
conditions after traumatic brain injury, neurosurgery and anesthesia;
neurotic disorders of various genesis, including after ionizing radiation;
to increase the body’s adaptive capacity in extreme situations;
to prevent mental fatigue;
in monotonous operator activity;
work in stressful conditions.
In ophthalmology
optic nerve atrophy;
optic neuritis of inflammatory or toxic-allergic etiology.
In pediatrics
as a nootropic agent in children aged 7 years and older for the treatment of minimal brain dysfunctions (including ADHD – attention deficit hyperactivity disorder).
Pharmacological action
A synthetic peptide that is an analogue of the ACTH4-10 fragment (methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline), completely devoid of hormonal activity. All amino acids are L-form.
It has an original mechanism of neurospecific action on the central nervous system. It is a synthetic analogue of corticotropin, which has nootropic properties and is completely devoid of hormonal activity. It affects the processes associated with the formation of memory and learning. It enhances attention during learning and information analysis, improves the consolidation of a memory trace in patients after neurosurgical interventions, traumatic brain injury, suffering from cerebrovascular diseases, incl. discirculatory encephalopathy; improves the body’s adaptation to hypoxia, cerebral ischemia, anesthesia and other damaging effects.
Practically non-toxic with single and long-term administration. Does not exhibit allergic, embryotoxic, teratogenic and mutagenic properties. Does not have a local irritant effect.
Drug interactions
Pharmaceutical
Based on the chemical structure, chemically incompatible combinations are not expected: it is quickly destroyed and does not enter the gastrointestinal tract.
Pharmacokinetic
Considering the chemical structure (heptapeptide – a synthetic analogue of ACTH, completely devoid of hormonal activity), the rate of absorption and the rate of entry into the blood, as well as the intranasal route of administration, the effect of other drugs on the pharmacokinetic parameters is not expected.
It is not recommended to take together with drugs that have a local vasoconstrictor effect when administered intranasally.
Composition:
Drug should be stored with tightly closed cap.
Semax in terms of 100% substance – 10 g, methyl parahydroxybenzoate (Nipagin) – 1 g, purified water
Contraindications:
-Acute mental conditions;
-Anxiety disorders;
-History of seizures;
-Children under 7 years of age;
-Hypersensitivity to the components of the drug.
Side effects: Prolonged use may cause mild irritation of the nasal mucosa.
Storage conditions and periods
Store in a dark place at a temperature not exceeding 10°C. Do not freeze. Store an opened bottle at a temperature not exceeding 25°C for no more than 30 days.






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